e-Health Centre (also referred to as CeZ or the Centre) a unit under the Polish Ministry of Health responsible for developing information systems, has undergone a significant transformation in the last 2-3 years, including the COVID-19 epidemic, which catalyzed the implementation of subsequent e-services and accelerated the development of e-health. The need to adapt the health care system to new conditions (including operating under a rigorous sanitary regime and the need to limit contacts) has shown that the development of e-health is a key and desirable direction of change in this area. The level of use for the provided IT solutions has also increased, which is important for the smooth implementation of further e-services. A strategy has been developed for the development of the e-Health Centre in order to maximize this potential in next years.