Chronic obstructive pulmonary disease (COPD) refers to a group of diseases associated with breathing-related problems that affect millions of people worldwide. COPD is very heterogeneous, necessitating personalised treatment and management approaches. However, due to extrapulmonary effects and comorbidities, patients often do not respond to pharmacological and non-pharmacological treatments. To address this problem, the EU-funded TOLIFE project proposes to develop an AI solution that processes daily life patient data captured by unobtrusive sensors. The AI-based platform will predict COPD exacerbations and assess health outcomes. Using a patient management tool, clinicians can then offer early and personalised treatment, improving quality of life of patients.